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Additional resources for Science (Vol. 305, No. 5690, September 2004)

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A. Knepper is in the Laboratory of Kidney and Electrolyte Metabolism, National Institutes of teins. However, structures of integral pro- the lipid bilayer is too slow for physiologiHealth, Bethesda, MD 20892, USA. gov P. Agre is in the Departments of loops are just now beginning to emerge. A get for regulating the passage of NH3. Both Biological Chemistry and Medicine, Johns Hopkins common strategy, and one adopted by functions may be important in the mamUniversity School of Medicine, Baltimore, MD 21205, USA.

Be expected to have flexible elements + + Ammonia (NH3) is a gas, but when disinvolved in translocation of the subNH4 H solved in water it exists predominantly as the strate. At the two ends of the pore, ammonium ion (NH4+) with a pKa of about 9 broader vestibules contain NH3 in under physiological conditions. For a bacequilibrium with NH4+. AmtB has at terium, NH3 is an important nutrient that its center a narrow hydrophobic pore Cytoplasm must be taken up from the surroundings to element about 20 Å in length, which provide a source of nitrogen for amino acid allows the passage of NH3 but not the The AmtB ammonia channel of E.

The issue of quantifying self-induction came to prominence in efforts to commercially run alternating-current generators (alternators) in parallel, as was done with the beltlinked alternators and steam generators at this Electric Lighting Station in West London (circa 1893). sumption. For the difficult task of measuring the self-induction of electrical machinery, no consensus was established until early in the 20th century. Gooday also shows, however, that even a seemingly simple measurement of electrical current was not universally standardized during the Victorian era, because scientists and engineers employed different amperemeters at different sites and for different purposes.

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