Download Handbook of psychiatric drugs by Lawrence J., M.D. Albers, Rhoda K., M.D. Hahn, Christopher, PDF

By Lawrence J., M.D. Albers, Rhoda K., M.D. Hahn, Christopher, M.D. Reist

This compact guide positive factors dosage, part impact, and drug interplay info for all psychiatric medicinal drugs. It comprises details that's important to the psychiatrist, internist, and pupil

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Carbamazepine may be helpful in treating certain impulse control disorders, such as those seen in patients with developmental disabilities. It may also be helpful to reduce symptoms of impulsivity and affective instability in patients with severe personality disorders. Carbamazepine may augment antidepressant treatment in depressed patients who are treatmentresistant. II. Pharmacology A. The mechanism of action of carbamazepine in psychiatric disorders is unknown. B. Carbamazepine is metabolized by the liver (CYP3A4).

Rash is most likely to occur in the first 4-6 weeks. C. Metabolic: Weight gain. D. GI: Nausea and vomiting. E. Psychiatric: Agitation, irritability anxiety, depression and mania. V. Drug Interactions A. Carbamazepine-induced enzyme induction will enhance lamotrigine metabolism, resulting in lower levels than expected. Lamotrigine will increase the levels of and metabolites of carbamazepine. B. Valproate will increase lamotrigine levels (as much as two times), and lamotrigine will decrease valproate levels slightly.

It is also widely used on an oral basis as a prn adjunct to fixed doses of antipsychotic medication. Pregnancy: Category D. References, see page 109. Non-Benzodiazepine Anxiolytics Buspirone (BuSpar) Category: Anxiolytic. Non-benzodiazepine, non-sedative hypnotic. Mechanism: Serotonin 1A agonist. Indications: Generalized Anxiety Disorder (GAD). May be used to augment antidepressant treatment of Major Depressive Disorder and Obsessive- Compulsive Disorder (OCD). Often useful in the treatment of aggression and agitation in dementia and in patients with developmental disabilities.

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