By George F Koob; Michael A Arends; Michel Le Moal
Drugs, habit, and the Brain explores the molecular, mobile, and neurocircuitry platforms within the mind which are accountable for drug habit. universal neurobiological parts are emphasised that supply novel insights into how the mind mediates the extreme worthwhile results of gear of abuse and the way it adjustments throughout the transition from preliminary drug use to compulsive drug use and dependancy. The ebook offers a close review of the pathophysiology of the ailment. the data supplied can be invaluable for neuroscientists within the box of habit, drug abuse therapy prone, and undergraduate and postgraduate scholars who're drawn to studying the varied results of substances of abuse at the brain.
- Full-color circuitry diagrams of mind areas implicated in every one level of the dependancy cycle
- Actual facts figures from unique assets illustrating key ideas and findings
- Introduction to uncomplicated neuropharmacology phrases and concepts
- Introduction to varied animal types used to check various points of drug use.
- Thorough overview of extant paintings at the neurobiology of addiction
Read or Download Drugs, addiction, and the brain PDF
Similar psychology & counseling books
The felony method calls for psychological well-being execs to supply learn summaries to help their reviews in baby custody circumstances. Contributions from best developmental researchers, attorneys, and clinicians describe how clinical facts is correctly utilized in courtroom. well timed and present, this publication is helping evaluators entry the easiest details to meet their tasks to their consumers and the courtroom.
Dr. Hersen has amassed during this exceptional 4-volume paintings the top resaerchers and clinicians in mental overview. This groundbreaking reference offers crucial info at the 4 significant sessions of mental evaluate tools, together with intelligence/neuropsychological, character (both goal and projective), behavioral, and industrial/organizational.
Additional resources for Drugs, addiction, and the brain
Modified with permission from Robbins TW, Everitt BJ. Central norepinephrine neurons and behavior. ) Psychopharmacology: The Fourth Generation of Progress. New York, Raven Press, 1995, pp. ] Basic Neurobiology of Addiction effects and dependence and addiction liability, however, are all largely mediated by the μ receptor. β-endorphin, the endogenous ligand for μ opioid receptors, is largely derived from proopiomelanocortin cells in the arcuate nucleus in the brain. It is distributed throughout the brainstem and basal forebrain and released from corticotropes in the anterior lobe of the pituitary.
15 Vasopressin localization. Schematic of the most prominent vasopressin-immunoreactive projections. AMB, ambiguus nucleus; BST, bed nucleus of the stria terminalis; CG, midbrain central gray; DM, dorsomedial nucleus of the hypothalamus; DR, dorsal raphe nucleus; DVC, dorsal vagal complex; HIP, ventral hippocampus; LC, locus coeruleus; LH; lateral habenular nucleus; LS; lateral septum; MA, medial nucleus of the amygdala; MP; medial preoptic area; OT, olfactory tubercle; ovlt; organum vasculosum laminae terminalis; PB, parabrachial nucleus; PV, periventricular nucleus of the hypothalamus; PVN, paraventricular nucleus; SCN, suprachiasmatic nucleus; SON, supraoptic nucleus; VSA, ventral septal area.
2000. Drug dependence, a chronic medical illness: implications for treatment, insurance, and outcomes evaluation. J. Am. Med. Assoc. 284, 1689–1695. , 1993. The neural basis of drug craving: an incentive-sensitization theory of addiction. Brain Res. Rev. 18, 247–291. , 1974. An opponent-process theory of motivation: 1. Temporal dynamics of affect. Psychol. Rev. 81, 119–145. , 1980. The opponent-process theory of acquired motivation: the costs of pleasure and the benefits of pain. Am. Psychol.