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By James L Bittle; Frederick A Murphy

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Extra resources for Advances in veterinary science and comparative medicine. Vol. 33, Vaccine biotechnology

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Feline Leukemia Virus (FeLV) FeLV commonly infects cats in urban areas, usually by the o r a l nasal route. Kittens under 6 months of age are particularly susceptible. About 1% of infected cats develop persistent anemia from which myeloproliferative disease and hypoplastic anemia may follow. The 34 J A M E S L. BITTLE A N D S U S I E M U I R immunosuppression caused by FeLV infection may predispose to severe chronic opportunistic infections. Because cats that develop neutralizing antibody are usually immune to infection, vaccines have been developed and tested with that goal in mind.

Vaccines for Gram-Negative Bacteria A. Entobacteria 1. Escherichia coli 2. Salmonella spp. 3. Yersinia pestis Ε. Brucella 1. Β. abortus 2. B. melitensis 3. B. ovis B. Pasteurella 1. P. multocida 2. P. haemolytica F. Campylobacter 1. C. fetus venerealis 2. C. fetus intestinalis C. Hemophilus 1. H. pleuropneumoniae 2. H. somnus G. D. Vibrio V. cholera H. Leptospira Bordetella 1. Β. pertussis 2. B. bronchiseptica I. J. A. spp. Neisseria N. meningitidis Rickettsia ENTEROBACTERIA Many members of this family are indigenous to the gastrointestinal tract with the fecal-oral route, often the most important mode of transmission in animals.

Brucella ovis bacterins in adjuvant, as well as B. melitensis vaccines, have been used to protect 50 J A M E S L. BITTLE A N D S U S I E M U I R animals from the disease B. , 1967). F. Campylobacter Pathogenic members of this genus are associated with venereal disease, fetal death, and abortion in cattle. 1. Campylobacter fetus venerealis This bacterium is transmitted to uninfected cattle by coitus or artificial insemination and is an obligate parasite of the genital tract. Immunization. , 1974; Hoerlin and Kramer, 1964), and prevents the carrier state (Wilkie and Winter, 1971).

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