Download Acid Catalysis in Modern Organic Synthesis, vol 1 by Hisashi Yamamoto, Kazuaki Ishihara PDF

By Hisashi Yamamoto, Kazuaki Ishihara

This two-volume set covers all new advancements and, furthermore, comprises the new notion of mixed Bronsted and Lewis acid catalysis, built by way of Hisashi Yamamoto himself. the wonderful editorial group has prepare an both best staff of professional authors, leading to a real treasure trove of crucial info -- making this a needs to for each chemist operating in natural chemistry and catalysis, in academia in addition to in undefined.

Show description

Read or Download Acid Catalysis in Modern Organic Synthesis, vol 1 PDF

Best organic books

The Total Synthesis of Natural Products

The whole Synthesis of typical items Edited by means of John ApSimon quantity Six The 6th quantity during this renowned sequence considers the entire synthesis of triterpenes, carbohydrates, fragrant steroids, pyrrole pigments and genes first stated through the interval from 1972 via 1982 during this sequence. 1984 (0 471-09900-7) 291 pp.

Organic Synthesis Using Transition Metals, Second Edition

Transition metals open up new possibilities for synthesis, simply because their technique of bonding and their response mechanisms vary from these of the weather of the s and p blocks. within the final twenty years the topic has mushroomed - proven reactions are seeing either technical advancements and lengthening numbers of functions, and new reactions are being constructed.

Metallocene Catalyzed Polymers. Materials, Properties, Processing & Markets

''. .. a truly functional ebook on plastic foams. .. '' - Polymer information

Additional resources for Acid Catalysis in Modern Organic Synthesis, vol 1

Sample text

2002) journal of the American Chem­ ical Society, 1 24, 9992 - 3 . (c) Ryu, D . H . , Corey, E . J . (2003) journal of the American Chemical Society, 125, 6388- 90. (d) Zhou, G . , Corey, E . J . (2003) Organic Letters, 5, 3979-82. J. (2004) journal of the Amer­ ican Chemical Society, 1 26, 4800 - 2 . (f) Ryu, D . H . , Zhou, G . , Corey, E . J . ( 2005) Organic Letters, 7, 1 6 3 3 - 6 . (g) Snyder, S . A . , Corey, E . J . (2006) journal of the American Chemical Society, 1 27, 740 - 2 . (h) Hong, S .

3 steps 98% ee . Scheme 1 25 Reagent-contro l ied d i astereoselectlve p ol yene cycl izatlon of (S) - 1 9 promoted by · (+)-1 8 (R) or (S) - 1 6. 1. 1 Combined Acid Catalysis 1 23 by ( R) - LBA (16) and the substrate control) in the diastereoselective polyene cycliza­ tion of racemic (20) (Scheme 1 . 26) [28a,b] . Although the total sequence for the asymmetric synthesis of ( - ) - (17) is the shortest, the reaction gave only 1 2 % yield of inseparable mixture of four products. / H (S)-20 + H rlG 6� � (R)-20 (1 equiv) ratio Tol u ene -78 °C, 24 h 12% yi e l d (R)-1 6 q:J ..

5 equivalent of ethyl or tert-butyl diazoacetate and various a-substituted acrolein derivatives afford chiral 2-pyrazolines with high 1. 1 9 E n a ntioselective 1 ,3-d i polar cycloaddition re­ actions of n itrones catalyzed by c h i ra l bi s-tita n i u m catalyst (12) . N2CHC02 Et + Me y CHO ll (1 . 20 E n a ntioselective 1 ,3-dipolar cycloaddition reac­ tions of diazoacetates catalyzed by (1 2) . enantioselectivities with 5 mol% of (12) as a chiral Lewis acid (84- 94% ee) . Interestingly, possible side reactions such as 1 ,2· and 1 ,4-addition of diazoacetates to a-substituted acroleins or cyclopropanation were somewhat suppressed under these reaction conditions .

Download PDF sample

Rated 4.29 of 5 – based on 50 votes